Hi Ronny
Check this thread:
https://scn.sap.com/thread/3681190
or this:
https://scn.sap.com/thread/3766357
In my case I had to change property of DI Proxy service (diproxy.properties file). It was:
SINGLECOMPANY=false
Also if you haven't done it before check the options for load balancing - details in PDF file attached to the note: http://service.sap.com/sap/support/notes/1993784
Kind regards,
Radek